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A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells
BACKGROUND: Kaposi’s sarcoma associated herpes virus (KSHV) is associated with tumors of endothelial and lymphoid origin. During latent infection, KSHV expresses miR-K12-11, an ortholog of the human tumor gene hsa-miR-155. Both gene products are microRNAs (miRNAs), which are important post-transcrip...
Autores principales: | Yang, Yajie, Boss, Isaac W, McIntyre, Lauren M, Renne, Rolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147158/ https://www.ncbi.nlm.nih.gov/pubmed/25106478 http://dx.doi.org/10.1186/1471-2164-15-668 |
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