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Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment
We have proposed that tolerance can be maintained through the induction, by Treg cells, of a tolerogenic microenvironment within tolerated tissues that inhibits effector cell activity but which supports the generation of further Treg cells by “infectious tolerance.” Two important components of this...
Autores principales: | Howie, Duncan, Waldmann, Herman, Cobbold, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147234/ https://www.ncbi.nlm.nih.gov/pubmed/25221554 http://dx.doi.org/10.3389/fimmu.2014.00409 |
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