A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas

MGMT expression is a critical determinant for therapeutic resistance to DNA alkylating agents. We previously demonstrated that MGMT expression is post-transcriptionally regulated by miR-181d and other miRNAs. Here, we performed a genome-wide screen to identify MGMT regulating miRNAs. Candidate miRNA...

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Detalles Bibliográficos
Autores principales: Kushwaha, Deepa, Ramakrishnan, Valya, Ng, Kimberly, Steed, Tyler, Nguyen, Thien, Futalan, Diahnn, Akers, Johnny C., Sarkaria, Jann, Jiang, Tao, Chowdhury, Dipanjan, Carter, Bob S., Chen, Clark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147303/
https://www.ncbi.nlm.nih.gov/pubmed/24994119

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