Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis

Although novel drugs have contributed immensely to improving outcomes of patients with multiple myeloma (MM), many patients develop drug resistance and ultimately succumb to MM. Here, we show that artesunate, an anti-malarial drug, reliably induces cell death in vitro in naïve as well as drug-resist...

Descripción completa

Detalles Bibliográficos
Autores principales: Papanikolaou, Xenofon, Johnson, Sarah, Garg, Tarun, Tian, Erming, Tytarenko, Ruslana, Zhang, Qing, Stein, Caleb, Barlogie, Bart, Epstein, Joshua, Heuck, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147310/
https://www.ncbi.nlm.nih.gov/pubmed/24948357

Ejemplares similares

Ejemplares similares