Metformin-induced metabolic reprogramming of chemoresistant ALDH(bright) breast cancer cells

Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDH(bright) cells) and their response to metformin, a promising anticancer metabolic...

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Detalles Bibliográficos
Autores principales: Cioce, Mario, Valerio, MariaCristina, Casadei, Luca, Pulito, Claudio, Sacconi, Andrea, Mori, Federica, Biagioni, Francesca, Manetti, Cesare, Muti, Paola, Strano, Sabrina, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147311/
https://www.ncbi.nlm.nih.gov/pubmed/24980829

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