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PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells

PLC-beta 1 (PLCβ1) inhibits in human K562 cells erythroid differentiation induced by mithramycin (MTH) by targeting miR-210 expression. Inhibition of miR-210 affects the erythroid differentiation pathway and it occurs to a greater extent in MTH-treated cells. Overexpression of PLCβ1 suppresses the d...

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Detalles Bibliográficos
Autores principales:	Bavelloni, Alberto, Poli, Alessandro, Fiume, Roberta, Blalock, William, Matteucci, Alessandro, Ramazzotti, Giulia, McCubrey, James A., Cocco, Lucio, Faenza, Irene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147318/ https://www.ncbi.nlm.nih.gov/pubmed/24962066

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