Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

We investigated the metabolic profile of cancer stem cells (CSC) isolated from patients with epithelial ovarian cancer. CSC overexpressed genes associated with glucose uptake, oxidative phosphorylation (OXPHOS), and fatty acid β-oxidation, indicating higher ability to direct pyruvate towards the Kre...

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Detalles Bibliográficos
Autores principales: Pastò, Anna, Bellio, Chiara, Pilotto, Giorgia, Ciminale, Vincenzo, Silic-Benussi, Micol, Guzzo, Giulia, Rasola, Andrea, Frasson, Chiara, Nardo, Giorgia, Zulato, Elisabetta, Nicoletto, Maria Ornella, Manicone, Mariangela, Indraccolo, Stefano, Amadori, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147325/
https://www.ncbi.nlm.nih.gov/pubmed/24946808

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