PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia

Pancreatic differentiation 2 (PD2), a PAF (RNA Polymerase II Associated Factor) complex subunit, is overexpressed in pancreatic cancer cells and has demonstrated potential oncogenic property. Here, we report that PD2/Paf1 expression was restricted to acinar cells in the normal murine pancreas, but i...

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Detalles Bibliográficos
Autores principales: Dey, Parama, Rachagani, Satyanarayana, Vaz, Arokia P., Ponnusamy, Moorthy P., Batra, Surinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147339/
https://www.ncbi.nlm.nih.gov/pubmed/24947474

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