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Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals
Target-specific agents used in melanoma are not curative, and chemokines are being implicated in drug-resistance to target-specific agents. Thus, the use of conventional agents in rationale combinations may result in optimization of therapy. Because histone deacetylases participate in tumor developm...
Autores principales: | Gatti, Laura, Sevko, Alexandra, Cesare, Michelandrea De, Arrighetti, Noemi, Manenti, Giacomo, Ciusani, Emilio, Verderio, Paolo, Ciniselli, Chiara M., Cominetti, Denis, Carenini, Nives, Corna, Elisabetta, Zaffaroni, Nadia, Rodolfo, Monica, Rivoltini, Licia, Umansky, Viktor, Perego, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147342/ https://www.ncbi.nlm.nih.gov/pubmed/24980831 |
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