Discovery of novel non-ATP competitive FGFR1 inhibitors and evaluation of their anti-tumor activity in non-small cell lung cancer in vitro and in vivo

Accumulating evidence suggests that high expression of FGFR1 is closely related to the development of lung cancer especially in non-small cell lung cancers (NSCLC), to which non-ATP competitive inhibitors represent an effective therapeutical approach due to their good specificity. Herein, a series o...

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Detalles Bibliográficos
Autores principales: Wu, Jianzhang, Ji, Jiansong, Weng, Bixia, Qiu, Peihong, Kanchana, Karvannan, Wei, Tao, Wang, Yi, Cai, Yuepiao, Li, Xiaokun, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147344/
https://www.ncbi.nlm.nih.gov/pubmed/24980830

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