The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM Repertoires

We have previously observed that all known potent broadly neutralizing antibodies (bnAbs) against HIV-1 are highly divergent from their putative germline predecessors in contrast to bnAbs against viruses causing acute infections such as henipaviruses and SARS CoV, which are much less divergent from...

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Detalles Bibliográficos
Autores principales: Prabakaran, Ponraj, Chen, Weizao, Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147355/
https://www.ncbi.nlm.nih.gov/pubmed/25221552
http://dx.doi.org/10.3389/fimmu.2014.00398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147355/
https://www.ncbi.nlm.nih.gov/pubmed/25221552
http://dx.doi.org/10.3389/fimmu.2014.00398

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