OA03.07. A comparative clinical study to evaluate the therapeutic effect of shivagutika in patients with H.I.V infection

PURPOSE: HIVAIDS is the most dreaded challenge that the today's medical world is facing! As patients do not have many options, they tend to look at ayurveda to help improve their condition clinical presentation of HIV is akin to the description of Rajayakshma characterized by involvement of multiple srotas and presenting with diarrhea, cough, fever and similar other symptoms. Shiva guttika is used here as a rasayana to improve the immunity. METHOD: A Single blind comparative clinical study with Pretest & Post test design. The patients were randomly categorized into two groups as shivagutika group and ART group consisting of 20 patients each Shivagutika group In this group the 20 patients were treated orally with shivagutika in a dose of 12 grams od, for 6 months ART group In this the patients were treated with ART for six months. RESULT: The criteria's selected for the evaluation like Cough, Dyspnoea, fever,body weight, HB%, ESR, CD4 count etc all were statistically analyzed. Following medication with shivagutika the value of cd4 count was 567 in comparison to initial value of 391. in the ART group the initial value of 417.6 increased to 447.6 following treatment. CONCLUSION: CD4 count affirms the therapeutic benefit of shivagutika in HIV infection /AIDS beyond doubt Various other vyadhi hara rasayanas can be used in the management of immuno compromised conditions and in reoccurant diseases.