PA02.10. A review on immunomodulator activity of some indiginious medical plants

PURPOSE: It has been estimated that about 6 laks infant and young children die from RSV annually, and if bacterial co infections are included this number may approach 10 laks deaths annually. More than 2 million deaths are estimated to result each year the world over as a consequence of diarrheal disease in children of under five years. This statistic shows that children are more vulnerable to infection because their immune system is less or under developed. At this age any intervention which could motivate their immune system, may prove boon to them. Ayurveda with its concept of Rasayana is holding various medicinal plants which are excellent immunomodulator and capable to reduce the morbidity status. METHOD: Peer review journals were searched to list all medicinal plants with immunomodulator activities, particularly acting on recurrent respiratory infection and recurrent diarrhoeal episodes. Only full texts in English were accepted for the present study. RESULT: Out of all researches Amalaki (Emblica officinalis), Ashwagandha(Withania somnifera), Yashtimadhu (Glycyrrhiza glabra), and Guduchi (Tinospora cordifolia) were found more potent to reduce morbidity rate. In which Amalaki is very cost effective, easily available, easily cultivated with highest immunomodulator properties. CONCLUSION: Recurrent respiratory tract infection and recurrent diarrhoeal episodes are major part of morbidity and Amalaki is a best option to reduce it.