Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects

Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, a...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyan, Ruan, Lifang, Peng, Donghai, Li, Lin, Sun, Ming, Yu, Ziniu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147579/
https://www.ncbi.nlm.nih.gov/pubmed/25068925
http://dx.doi.org/10.3390/toxins6082229
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author Liu, Xiaoyan
Ruan, Lifang
Peng, Donghai
Li, Lin
Sun, Ming
Yu, Ziniu
author_facet Liu, Xiaoyan
Ruan, Lifang
Peng, Donghai
Li, Lin
Sun, Ming
Yu, Ziniu
author_sort Liu, Xiaoyan
collection PubMed
description Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C(22)H(32)O(19)N(5)P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided.
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spelling pubmed-41475792014-08-28 Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects Liu, Xiaoyan Ruan, Lifang Peng, Donghai Li, Lin Sun, Ming Yu, Ziniu Toxins (Basel) Review Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C(22)H(32)O(19)N(5)P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided. MDPI 2014-07-25 /pmc/articles/PMC4147579/ /pubmed/25068925 http://dx.doi.org/10.3390/toxins6082229 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Liu, Xiaoyan
Ruan, Lifang
Peng, Donghai
Li, Lin
Sun, Ming
Yu, Ziniu
Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title_full Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title_fullStr Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title_full_unstemmed Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title_short Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
title_sort thuringiensin: a thermostable secondary metabolite from bacillus thuringiensis with insecticidal activity against a wide range of insects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147579/
https://www.ncbi.nlm.nih.gov/pubmed/25068925
http://dx.doi.org/10.3390/toxins6082229
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