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AKR1C3 Overexpression Mediates Methotrexate Resistance in Choriocarcinoma Cells

Background: Chemotherapy is typically used to treat choriocarcinoma, but a small proportion of tumors develop resistance to chemotherapy. Similarly, methotrexate (MTX) is a first-line chemotherapy used to treat choriocarcinoma; although ~30% of patients are drug-resistant for MTX mono-therapy. Thus,...

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Detalles Bibliográficos
Autores principales:	Zhao, Jing, Xiang, Yang, Xiao, Changji, Guo, Peng, Wang, Dan, Liu, Ying, Shen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147634/ https://www.ncbi.nlm.nih.gov/pubmed/25170291 http://dx.doi.org/10.7150/ijms.9239

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