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Heterogeneity of Osteosarcoma Cell Lines Led to Variable Responses in Reprogramming

Four osteosarcoma cell lines, Saos-2, MG-63, G-292 and U-2 OS, were reprogrammed to pluripotent state using Yamanaka factors retroviral transduction method. Embryonic stem cell (ESC)-like clusters started to appear between 15 to 20 days post transduction. Morphology of the colonies resembled that of...

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Detalles Bibliográficos
Autores principales: Choong, Pei Feng, Teh, Hui Xin, Teoh, Hoon Koon, Ong, Han Kiat, Choo, Kong Bung, Sugii, Shigeki, Cheong, Soon Keng, Kamarul, Tunku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147642/
https://www.ncbi.nlm.nih.gov/pubmed/25170299
http://dx.doi.org/10.7150/ijms.8281