Cargando…
Fiber-Modified Adenovirus for Central Nervous System Parkinson’s Disease Gene Therapy
Gene-based therapies for neurological diseases continue to develop briskly. As disease mechanisms are elucidated, flexible gene delivery platforms incorporating transcriptional regulatory elements, therapeutic genes and targeted delivery are required for the safety and efficacy of these approaches....
Autores principales: | Lewis, Travis B., Glasgow, Joel N., Harms, Ashley S., Standaert, David G., Curiel, David T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147696/ https://www.ncbi.nlm.nih.gov/pubmed/25196484 http://dx.doi.org/10.3390/v6083293 |
Ejemplares similares
-
Transduction of Brain Dopamine Neurons by Adenoviral Vectors Is Modulated by CAR Expression: Rationale for Tropism Modified Vectors in PD Gene Therapy
por: Lewis, Travis B., et al.
Publicado: (2010) -
Efficient Gene Transduction by RGB‐fiber Modified Recombinant Adenovirus into Dendritic Cells
por: Asada‐Mikami, Rumiko, et al.
Publicado: (2001) -
An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene Transfer
por: Kim, Julius W., et al.
Publicado: (2013) -
A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain Antibody
por: Glasgow, Joel N., et al.
Publicado: (2009) -
Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease
por: Thome, Aaron D., et al.
Publicado: (2015)