Immunogenetics of Small Ruminant Lentiviral Infections

The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs...

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Autores principales: Stonos, Nancy, Wootton, Sarah K., Karrow, Niel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147697/
https://www.ncbi.nlm.nih.gov/pubmed/25153344
http://dx.doi.org/10.3390/v6083311
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author Stonos, Nancy
Wootton, Sarah K.
Karrow, Niel
author_facet Stonos, Nancy
Wootton, Sarah K.
Karrow, Niel
author_sort Stonos, Nancy
collection PubMed
description The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed light on the possible immune mechanisms that control or lead to disease progression. This review will focus on the host immune response to HIV-1 and SRLV, and will discuss the possibility of breeding for enhanced SRLV disease resistance.
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spelling pubmed-41476972014-08-28 Immunogenetics of Small Ruminant Lentiviral Infections Stonos, Nancy Wootton, Sarah K. Karrow, Niel Viruses Review The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed light on the possible immune mechanisms that control or lead to disease progression. This review will focus on the host immune response to HIV-1 and SRLV, and will discuss the possibility of breeding for enhanced SRLV disease resistance. MDPI 2014-08-22 /pmc/articles/PMC4147697/ /pubmed/25153344 http://dx.doi.org/10.3390/v6083311 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Stonos, Nancy
Wootton, Sarah K.
Karrow, Niel
Immunogenetics of Small Ruminant Lentiviral Infections
title Immunogenetics of Small Ruminant Lentiviral Infections
title_full Immunogenetics of Small Ruminant Lentiviral Infections
title_fullStr Immunogenetics of Small Ruminant Lentiviral Infections
title_full_unstemmed Immunogenetics of Small Ruminant Lentiviral Infections
title_short Immunogenetics of Small Ruminant Lentiviral Infections
title_sort immunogenetics of small ruminant lentiviral infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147697/
https://www.ncbi.nlm.nih.gov/pubmed/25153344
http://dx.doi.org/10.3390/v6083311
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