Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding

Expression and secretion of apolipoprotein A-I (apoA-I) by cultured liver cells can be markedly stimulated by triazolodiazepines (TZDs). It has been shown previously that the thieno-TZD Ro 11-1464 increases plasma levels of apoA-I and in vivomacrophage reverse cholesterol transport in mice. However,...

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Detalles Bibliográficos
Autores principales: Kempen, Herman J, Bellus, Daniel, Fedorov, Oleg, Nicklisch, Silke, Filippakopoulos, Panagis, Picaud, Sarah, Knapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147775/
https://www.ncbi.nlm.nih.gov/pubmed/25278768
http://dx.doi.org/10.4137/Lpi.s13258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147775/
https://www.ncbi.nlm.nih.gov/pubmed/25278768
http://dx.doi.org/10.4137/Lpi.s13258

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