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Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding
Expression and secretion of apolipoprotein A-I (apoA-I) by cultured liver cells can be markedly stimulated by triazolodiazepines (TZDs). It has been shown previously that the thieno-TZD Ro 11-1464 increases plasma levels of apoA-I and in vivomacrophage reverse cholesterol transport in mice. However,...
Autores principales: | Kempen, Herman J, Bellus, Daniel, Fedorov, Oleg, Nicklisch, Silke, Filippakopoulos, Panagis, Picaud, Sarah, Knapp, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147775/ https://www.ncbi.nlm.nih.gov/pubmed/25278768 http://dx.doi.org/10.4137/Lpi.s13258 |
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