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Estimating the activity of transcription factors by the effect on their target genes

Motivation: Understanding regulation of transcription is central for elucidating cellular regulation. Several statistical and mechanistic models have come up the last couple of years explaining gene transcription levels using information of potential transcriptional regulators as transcription facto...

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Detalles Bibliográficos
Autores principales: Schacht, Theresa, Oswald, Marcus, Eils, Roland, Eichmüller, Stefan B., König, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147899/
https://www.ncbi.nlm.nih.gov/pubmed/25161226
http://dx.doi.org/10.1093/bioinformatics/btu446