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DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution

BACKGROUND: Methyl-CpG binding protein 2 (MECP2) is a protein that specifically binds methylated DNA, thus regulating transcription and chromatin organization. Mutations in the gene have been identified as the principal cause of Rett syndrome, a severe neurological disorder. Although the role of MEC...

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Detalles Bibliográficos
Autores principales: Song, Congdi, Feodorova, Yana, Guy, Jacky, Peichl, Leo, Jost, Katharina Laurence, Kimura, Hiroshi, Cardoso, Maria Cristina, Bird, Adrian, Leonhardt, Heinrich, Joffe, Boris, Solovei, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148084/
https://www.ncbi.nlm.nih.gov/pubmed/25170345
http://dx.doi.org/10.1186/1756-8935-7-17