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A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer

JMJD2C is a candidate oncogene that encodes a histone lysine demethylase with the ability to demethylate the lysine 9 residue of histone H3 (H3K9). The expression levels of JMJD2C are associated with tumor development and clinical outcome. Here we identify JMJD2C as a new substrate for caspase-3. JM...

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Detalles Bibliográficos
Autores principales: Hong, Qi, Yu, Sanjian, Yang, Yu, Liu, Guangyu, Shao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148098/
https://www.ncbi.nlm.nih.gov/pubmed/24952432