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A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer
JMJD2C is a candidate oncogene that encodes a histone lysine demethylase with the ability to demethylate the lysine 9 residue of histone H3 (H3K9). The expression levels of JMJD2C are associated with tumor development and clinical outcome. Here we identify JMJD2C as a new substrate for caspase-3. JM...
Autores principales: | Hong, Qi, Yu, Sanjian, Yang, Yu, Liu, Guangyu, Shao, Zhiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148098/ https://www.ncbi.nlm.nih.gov/pubmed/24952432 |
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