Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

Endoplasmic reticulum stress from unfolded proteins is associated with the proliferation of pancreatic tumor cells, making the many regulatory molecules of this pathway appealing targets for therapy. The objective of our study was to assess potential therapeutic efficacy of inhibitors of unfolded pr...

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Detalles Bibliográficos
Autores principales: Chien, Wenwen, Ding, Ling-Wen, Sun, Qiao-Yang, Torres-Fernandez, Lucia A, Tan, Siew Zhuan, Xiao, Jinfen, Lim, Su Lin, Garg, Manoj, Lee, Kian Leong, Kitajima, Shojiro, Takao, Sumiko, Leong, Wei Zhong, Sun, Haibo, Tokatly, Itay, Poellinger, Lorenz, Gery, Sigal, Koeffler, Phillip H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148107/
https://www.ncbi.nlm.nih.gov/pubmed/24952679

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