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Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation
Cancer cells with self-renewal and tumor-initiating capacity, either quiescent (cancer stem cells, CSCs) or proliferating (cancer stem-like cells, CSLCs), are now deemed responsible for the pervasive therapy resistance of pancreatic cancer, one of the deadliest human cancers characterized by high pr...
Autores principales: | Okada, Masashi, Shibuya, Keita, Sato, Atsushi, Seino, Shizuka, Suzuki, Shuhei, Seino, Manabu, Kitanaka, Chifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148125/ https://www.ncbi.nlm.nih.gov/pubmed/24947996 |
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