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H-Ras regulation of TRAIL death receptor mediated apoptosis

TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis through the death receptors (DRs) 4 and/or 5 expressed on the cell surface. Multiple clinical trials are underway to evaluate the antitumor activity of recombinant human TRAIL and agonistic antibodies to DR4 or DR5. However, their thera...

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Detalles Bibliográficos
Autores principales:	Chen, Jun-Jie, Bozza, William P., Di, Xu, Zhang, Yaqin, Hallett, William, Zhang, Baolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148127/ https://www.ncbi.nlm.nih.gov/pubmed/25026275

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