RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth

Partial loss of large ribosomal subunit protein 24 (RPL24) function is known to protect mice against Akt or Myc-driven cancers, in part via translational inhibition of a subset of cap(eIF4E)-dependently translated mRNAs. The role of RPL24 in human malignancies is unknown. By analyzing a public datas...

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Detalles Bibliográficos
Autores principales: Wilson-Edell, Kathleen A., Kehasse, Amanuel, Scott, Gary K., Yau, Christina, Rothschild, Daniel E., Schilling, Birgit, Gabriel, Bianca S., Yevtushenko, Mariya A., Hanson, Ingrid M., Held, Jason M., Gibson, Bradford W., Benz, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148130/
https://www.ncbi.nlm.nih.gov/pubmed/24970821

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