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Central P2Y(12) receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents
In this study the role of P2Y(12) receptors (P2Y(12)R) was explored in rodent models of inflammatory and neuropathic pain and in acute thermal nociception. In correlation with their activity to block the recombinant human P2Y(12)R, the majority of P2Y(12)R antagonists alleviated mechanical hyperalge...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148180/ https://www.ncbi.nlm.nih.gov/pubmed/24971933 http://dx.doi.org/10.1016/j.nbd.2014.06.011 |