Central P2Y(12) receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

In this study the role of P2Y(12) receptors (P2Y(12)R) was explored in rodent models of inflammatory and neuropathic pain and in acute thermal nociception. In correlation with their activity to block the recombinant human P2Y(12)R, the majority of P2Y(12)R antagonists alleviated mechanical hyperalge...

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Detalles Bibliográficos
Autores principales: Horváth, Gergely, Gölöncsér, Flóra, Csölle, Cecilia, Király, Kornél, Andó, Rómeó D., Baranyi, Mária, Koványi, Bence, Máté, Zoltán, Hoffmann, Kristina, Algaier, Irina, Baqi, Younis, Müller, Christa E., Von Kügelgen, Ivar, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148180/
https://www.ncbi.nlm.nih.gov/pubmed/24971933
http://dx.doi.org/10.1016/j.nbd.2014.06.011

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