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Possible Role of Interleukin-1β in Type 2 Diabetes Onset and Implications for Anti-inflammatory Therapy Strategies

Increasing evidence of a role of chronic inflammation in type 2 diabetes progression has led to the development of therapies targeting the immune system. We develop a model of interleukin-1β dynamics in order to explain principles of disease onset. The parameters in the model are derived from in vit...

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Detalles Bibliográficos
Autores principales:	Zhao, Gang, Dharmadhikari, Gitanjali, Maedler, Kathrin, Meyer-Hermann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148195/ https://www.ncbi.nlm.nih.gov/pubmed/25167060 http://dx.doi.org/10.1371/journal.pcbi.1003798

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