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Integration of UPR(ER) and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

The Unfolded Protein Response of the endoplasmic reticulum (UPR(ER)) controls proteostasis by adjusting the protein folding capacity of the ER to environmental and cell-intrinsic conditions. In metazoans, loss of proteostasis results in degenerative and proliferative diseases and cancers. The cellul...

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Detalles Bibliográficos
Autores principales:	Wang, Lifen, Zeng, Xiankun, Ryoo, Hyung Don, Jasper, Heinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148219/ https://www.ncbi.nlm.nih.gov/pubmed/25166757 http://dx.doi.org/10.1371/journal.pgen.1004568

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