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DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia

p120-catenin (p120) modulates adherens junction (AJ) dynamics by controlling the stability of classical cadherins. Among all p120 isoforms, p120-3A and p120-1A are the most prevalent. Both stabilize cadherins, but p120-3A is preferred in epithelia, whereas p120-1A takes precedence in neurons, fibrob...

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Detalles Bibliográficos
Autores principales: Markham, Nicholas O., Doll, Caleb A., Dohn, Michael R., Miller, Rachel K., Yu, Huapeng, Coffey, Robert J., McCrea, Pierre D., Gamse, Joshua T., Reynolds, Albert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148249/
https://www.ncbi.nlm.nih.gov/pubmed/25009281
http://dx.doi.org/10.1091/mbc.E13-08-0492