Case for diagnosis()

We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects...

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Autores principales: Maquiné, Gustavo Ávila, Maroja, Maria de Fátima, Mesquita, Cristina Rabello, de Sousa, Petra Pereira, de Morais, Patrícia Motta, Talhari, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2014
Materias:
What is your Diagnosis?
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148291/
https://www.ncbi.nlm.nih.gov/pubmed/25054764
http://dx.doi.org/10.1590/abd1806-4841.20142955
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author Maquiné, Gustavo Ávila
Maroja, Maria de Fátima
Mesquita, Cristina Rabello
de Sousa, Petra Pereira
de Morais, Patrícia Motta
Talhari, Carolina
author_facet Maquiné, Gustavo Ávila
Maroja, Maria de Fátima
Mesquita, Cristina Rabello
de Sousa, Petra Pereira
de Morais, Patrícia Motta
Talhari, Carolina
author_sort Maquiné, Gustavo Ávila
collection PubMed
description We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment.
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spelling pubmed-41482912014-09-04 Case for diagnosis() Maquiné, Gustavo Ávila Maroja, Maria de Fátima Mesquita, Cristina Rabello de Sousa, Petra Pereira de Morais, Patrícia Motta Talhari, Carolina An Bras Dermatol What is your Diagnosis? We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment. Sociedade Brasileira de Dermatologia 2014 /pmc/articles/PMC4148291/ /pubmed/25054764 http://dx.doi.org/10.1590/abd1806-4841.20142955 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle What is your Diagnosis?
Maquiné, Gustavo Ávila
Maroja, Maria de Fátima
Mesquita, Cristina Rabello
de Sousa, Petra Pereira
de Morais, Patrícia Motta
Talhari, Carolina
Case for diagnosis()
title Case for diagnosis()
title_full Case for diagnosis()
title_fullStr Case for diagnosis()
title_full_unstemmed Case for diagnosis()
title_short Case for diagnosis()
title_sort case for diagnosis()
topic What is your Diagnosis?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148291/
https://www.ncbi.nlm.nih.gov/pubmed/25054764
http://dx.doi.org/10.1590/abd1806-4841.20142955
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AT talharicarolina casefordiagnosis

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