TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions

Neurofibromatosis type 1 (NF1) caused by NF1 gene mutation is a commonly inherited autosomal dominant disorder. Malignant peripheral nerve sheath tumors (MPNSTs), a type of aggressive sarcoma, are a major cause of mortality in NF1 patients. The malignant transformation of benign plexiform neurofibro...

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Detalles Bibliográficos
Autores principales: PARK, GUN-HOO, LEE, SU-JIN, YIM, HYUNE, HAN, JAE-HO, KIM, HYON J., SOHN, YOUNG-BAE, KO, JUNG MIN, JEONG, SEON-YONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148385/
https://www.ncbi.nlm.nih.gov/pubmed/25109740
http://dx.doi.org/10.3892/or.2014.3379

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