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From Synovial Tissue to Peripheral Blood: Myeloid Related Protein 8/14 Is a Sensitive Biomarker for Effective Treatment in Early Drug Development in Patients with Rheumatoid Arthritis

OBJECTIVE: The change in number of CD68-positive sublining macrophages in serial synovial biopsies has been successfully used to discriminate on the group level between effective and ineffective treatment during early drug development in rheumatoid arthritis (RA) patients. Measurement of a soluble b...

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Detalles Bibliográficos
Autores principales: Choi, Ivy Y., Gerlag, Danielle M., Holzinger, Dirk, Roth, Johannes, Tak, Paul P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148438/
https://www.ncbi.nlm.nih.gov/pubmed/25166859
http://dx.doi.org/10.1371/journal.pone.0106253