Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells Is Associated with Lack of Progression in Viremic Individuals

A rare subset of HIV-infected individuals, designated viremic non-progressors (VNP), remain asymptomatic and maintain normal levels of CD4+ T-cells despite persistently high viremia. To identify mechanisms potentially responsible for the VNP phenotype, we compared VNPs (average >9 years of HIV in...

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Detalles Bibliográficos
Autores principales: Klatt, Nichole R., Bosinger, Steven E., Peck, Melicent, Richert-Spuhler, Laura E., Heigele, Anke, Gile, Jillian P., Patel, Nirav, Taaffe, Jessica, Julg, Boris, Camerini, David, Torti, Carlo, Martin, Jeffrey N., Deeks, Steven G., Sinclair, Elizabeth, Hecht, Frederick M., Lederman, Michael M., Paiardini, Mirko, Kirchhoff, Frank, Brenchley, Jason M., Hunt, Peter W., Silvestri, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148445/
https://www.ncbi.nlm.nih.gov/pubmed/25167059
http://dx.doi.org/10.1371/journal.ppat.1004345

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