Adult Thymus Contains FoxN1(−) Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic Epithelial Lineages

Within the thymus, two major thymic epithelial cell (TEC) subsets—cortical and medullary TECs—provide unique structural and functional niches for T cell development and establishment of central tolerance. Both lineages are believed to originate from a common progenitor cell, yet the cellular and mol...

Descripción completa

Detalles Bibliográficos
Autores principales: Ucar, Ahmet, Ucar, Olga, Klug, Paula, Matt, Sonja, Brunk, Fabian, Hofmann, Thomas G., Kyewski, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148705/
https://www.ncbi.nlm.nih.gov/pubmed/25148026
http://dx.doi.org/10.1016/j.immuni.2014.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148705/
https://www.ncbi.nlm.nih.gov/pubmed/25148026
http://dx.doi.org/10.1016/j.immuni.2014.07.005

Ejemplares similares