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Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment
Environmental enrichment produces protective addiction and depression phenotypes in rats. ΔFosB is a transcription factor that regulates reward in the brain and is induced by psychological stress as well as drugs of abuse. However, the role played by ΔFosB in the protective phenotypes of environment...
Autores principales: | Zhang, Yafang, Crofton, Elizabeth J., Li, Dingge, Lobo, Mary Kay, Fan, Xiuzhen, Nestler, Eric J., Green, Thomas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148937/ https://www.ncbi.nlm.nih.gov/pubmed/25221490 http://dx.doi.org/10.3389/fnbeh.2014.00297 |
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