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Sox2 acts as a transcriptional repressor in neural stem cells

BACKGROUND: The transcription factor, Sox2, is central to the behaviour of neural stem cells. It is also one of the key embryonic stem cell factors that, when overexpressed can convert somatic cells into induced pluripotent cells. Although generally studied as a transcriptional activator, recent evi...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Ru, Laghari, Zulfiqar A, Novoa, Carolina A, Hughes, Jaime, Webster, Jamie RM, Goodwin, Paul E, Wheatley, Sally P, Scotting, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148960/
https://www.ncbi.nlm.nih.gov/pubmed/25103589
http://dx.doi.org/10.1186/1471-2202-15-95