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Sox2 acts as a transcriptional repressor in neural stem cells
BACKGROUND: The transcription factor, Sox2, is central to the behaviour of neural stem cells. It is also one of the key embryonic stem cell factors that, when overexpressed can convert somatic cells into induced pluripotent cells. Although generally studied as a transcriptional activator, recent evi...
Autores principales: | Liu, Yu-Ru, Laghari, Zulfiqar A, Novoa, Carolina A, Hughes, Jaime, Webster, Jamie RM, Goodwin, Paul E, Wheatley, Sally P, Scotting, Paul J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148960/ https://www.ncbi.nlm.nih.gov/pubmed/25103589 http://dx.doi.org/10.1186/1471-2202-15-95 |
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