Cargando…

GLP-1 (7–36) amide restores myocardial insulin sensitivity and prevents the progression of heart failure in senescent beagles

BACKGROUND: We previously demonstrated that older beagles have impaired whole body and myocardial insulin responsiveness (MIR), and that glucagon-like peptide-1 (GLP-1 [7–36] amide) improves MIR in young beagles with dilated cardiomyopathy (DCM). Here, we sought to determine if aging alone predispos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Melissa, Angeli, Franca S, Shen, You-tang, Shannon, Richard P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149213/ https://www.ncbi.nlm.nih.gov/pubmed/25078106 http://dx.doi.org/10.1186/s12933-014-0115-x

Ejemplares similares

GLP-1(28-36)amide, a Long Ignored Peptide Revisited
por: Zhou, Bilan, et al.
Publicado: (2014)

Combination of Peptide YY(3–36) with GLP-1(7–36 amide) Causes an Increase in First-Phase Insulin Secretion after IV Glucose
por: Tan, Tricia M., et al.
Publicado: (2014)

GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation
por: Katsurada, Kenichi, et al.
Publicado: (2020)

Allosteric Modulation of the Activity of the Glucagon-like Peptide-1 (GLP-1) Metabolite GLP-1 9–36 Amide at the GLP-1 Receptor
por: Li, Naichang, et al.
Publicado: (2012)

Improving Imputation Quality in BEAGLE for Crop and Livestock Data
por: Pook, Torsten, et al.
Publicado: (2019)

Metabolically-inactive glucagon-like peptide-1(9–36)amide confers selective protective actions against post-myocardial infarction remodelling
por: Robinson, Emma, et al.
Publicado: (2016)

Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects
por: Sathananthan, Matheni, et al.
Publicado: (2013)

GLP-1(28-36)amide, the Glucagon-like peptide-1 metabolite: friend, foe, or pharmacological folly?
por: Taing, Meng-Wong, et al.
Publicado: (2014)

The Gut Hormones PYY(3-36) and GLP-1(7-36 amide) Reduce Food Intake and Modulate Brain Activity in Appetite Centers in Humans
por: De Silva, Akila, et al.
Publicado: (2011)

GLP-1(32-36)amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice
por: Tomas, Eva, et al.
Publicado: (2015)

Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
por: Hausenloy, Derek J, et al.
Publicado: (2013)

Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects. Diabetes 2013;62:2752–2756
por: Sathananthan, M, et al.
Publicado: (2013)

Beagle put-down\ESA recognizes systemic failures in Beagle 2 as UK tries for more funding
por: Barrielondon, Douglas
Publicado: (2004)

Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat
por: Bao, Weike, et al.
Publicado: (2013)

Caenorhabditis elegans glp-4 Encodes a Valyl Aminoacyl tRNA Synthetase
por: Rastogi, Suchita, et al.
Publicado: (2015)

GLP-1 analog liraglutide-induced cardiac dysfunction due to energetic starvation in heart failure with non-diabetic dilated cardiomyopathy
por: Shiraki, Aya, et al.
Publicado: (2019)

Dissociation of GLP-1 and insulin association with food processing in the brain: GLP-1 sensitivity despite insulin resistance in obese humans
por: Heni, Martin, et al.
Publicado: (2015)

Cost-effectiveness of GLP-1 receptor agonists versus insulin for the treatment of type 2 diabetes: a real-world study and systematic review
por: Yang, Chen-Yi, et al.
Publicado: (2021)

Acute effects of glucagon‐like peptide‐1, GLP‐1(9–36 amide), and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers
por: Bremholm, Lasse, et al.
Publicado: (2017)

Cardioprotective effects of GLP‐1(28‐36a): A degraded metabolite or GLP‐1’s better half?
por: Liu, Yangyang, et al.
Publicado: (2020)

GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling
por: Chang, Ching-Chi, et al.
Publicado: (2018)

Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction
por: Karwi, Qutuba G., et al.
Publicado: (2019)

Cardiovascular outcomes after initiating GLP-1 receptor agonist or basal insulin for the routine treatment of type 2 diabetes: a region-wide retrospective study
por: Longato, Enrico, et al.
Publicado: (2021)

Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans
por: Piotrowski, Katja, et al.
Publicado: (2013)

BLX‐1002 restores glucose sensitivity and enhances insulin secretion stimulated by GLP‐1 and sulfonylurea in type 2 diabetic pancreatic islets
por: Zhang, Qimin, et al.
Publicado: (2014)

The Bafut beagles
por: Durrell, Gerald, 1925-1995
Publicado: (1958)

Darwin and the Beagle /
por: Moorehead, Alan, 1910-1983
Publicado: (1969)

El beagle /
por: Capra, Ernesto
Publicado: (1997)

Beagle pack
por: Barrie, D
Publicado: (2004)

The voyage of the Beagle /
por: Darwin, Charles, 1809-1882
Publicado: (1909)

Ingestion of coffee polyphenols increases postprandial release of the active glucagon-like peptide-1 (GLP-1(7–36)) amide in C57BL/6J mice
por: Fujii, Yoshie, et al.
Publicado: (2015)

Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
por: Hodson, Aimee E., et al.
Publicado: (2015)

meso-3,6-Dioxopiperazine-2,5-diacetamide
por: Li, Ping, et al.
Publicado: (2011)

Diacylglycerol kinase ζ inhibits myocardial atrophy and restores cardiac dysfunction in streptozotocin-induced diabetes mellitus
por: Bilim, Olga, et al.
Publicado: (2008)

Long-term administration of prednisolone: Effects on the myocardial tissue of healthy beagle dogs
por: TANAKA, Sachiyo, et al.
Publicado: (2020)

Meep, a Novel Regulator of Insulin Signaling, Supports Development and Insulin Sensitivity via Maintenance of Protein Homeostasis in Drosophila melanogaster
por: Pereira, Matthew T., et al.
Publicado: (2020)

Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance
por: Roy, Debasmita, et al.
Publicado: (2018)

The Length of the Shortest Telomere as the Major Determinant of the Onset of Replicative Senescence
por: Xu, Zhou, et al.
Publicado: (2013)

Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster
por: Parker, Grace A., et al.
Publicado: (2020)

BeagleBone cookbook
por: Yoder, Mark A, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vgks5f3578i3uteimn5rducc4m