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Diagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients

BACKGROUND: The PIK3CA gene mutation was found to associate with prognosis and might affect molecular targeted therapy in esophageal carcinoma (EC). The aim of this study is to compare different methods for analyzing the PIK3CA gene mutation in EC. METHODS: Genomic DNA was extracted from 106 surgica...

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Detalles Bibliográficos
Autores principales: Ming, Zizhen, Jiang, Dongxian, Hu, Qin, Li, Xiaojing, Huang, Jie, Xu, Yifan, Liu, Yalan, Xu, Chen, Hua, Xiuguo, Hou, Yingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149237/
https://www.ncbi.nlm.nih.gov/pubmed/25106743
http://dx.doi.org/10.1186/s13000-014-0153-4