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Wnts Enhance Neurotrophin-Induced Neuronal Differentiation in Adult Bone-Marrow-Derived Mesenchymal Stem Cells via Canonical and Noncanonical Signaling Pathways

Wnts were previously shown to regulate the neurogenesis of neural stem or progenitor cells. Here, we explored the underlying molecular mechanisms through which Wnt signaling regulates neurotrophins (NTs) in the NT-induced neuronal differentiation of human mesenchymal stem cells (hMSCs). NTs can incr...

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Detalles Bibliográficos
Autores principales: Tsai, Hung-Li, Deng, Wing-Ping, Lai, Wen-Fu Thomas, Chiu, Wen-Ta, Yang, Charn-Bing, Tsai, Yu-Hui, Hwang, Shiaw-Min, Renshaw, Perry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149376/
https://www.ncbi.nlm.nih.gov/pubmed/25170755
http://dx.doi.org/10.1371/journal.pone.0104937