Molecular Network Analysis Suggests a Logical Hypothesis for the Pathological Role of C9orf72 in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

BACKGROUND: Expanded GGGGCC hexanucleotide repeats, ranging from hundreds to thousands in number, located in the noncoding region of the chromosome 9 open reading frame 72 (C9orf72) gene represent the most common genetic abnormality for familial and sporadic amyotrophic lateral sclerosis (ALS) and f...

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Detalles Bibliográficos
Autores principales: Satoh, Jun-ichi, Yamamoto, Yoji, Kitano, Shouta, Takitani, Mika, Asahina, Naohiro, Kino, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149381/
https://www.ncbi.nlm.nih.gov/pubmed/25210488
http://dx.doi.org/10.4137/JCNSD.S18103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149381/
https://www.ncbi.nlm.nih.gov/pubmed/25210488
http://dx.doi.org/10.4137/JCNSD.S18103

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