Use of an In Vivo FTA Assay to Assess the Magnitude, Functional Avidity and Epitope Variant Cross-Reactivity of T Cell Responses Following HIV-1 Recombinant Poxvirus Vaccination

Qualitative characteristics of cytotoxic CD8(+) T cells (CTLs) are important in measuring the effectiveness of CTLs in controlling HIV-1 infections. Indeed, in recent studies patients who are naturally resistant to HIV-1 infections have been shown to possess CTLs that are of high functional avidity...

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Detalles Bibliográficos
Autores principales: Wijesundara, Danushka K., Ranasinghe, Charani, Jackson, Ronald J., Lidbury, Brett A., Parish, Christopher R., Quah, Benjamin J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149432/
https://www.ncbi.nlm.nih.gov/pubmed/25170620
http://dx.doi.org/10.1371/journal.pone.0105366

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