Cargando…

Intracellular uptake of etoposide-loaded solid lipid nanoparticles induces an enhancing inhibitory effect on gastric cancer through mitochondria-mediated apoptosis pathway

The objective of this study was to prepare and characterize etoposide (VP16)-loaded solid lipid nanoparticles (SLNs) and evaluate their antitumor activity in vitro. VP16-SLNs were prepared using emulsification and low-temperature solidification methods. The physicochemical properties of the VP16-SLN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jiao, Zhu, Rongrong, Sun, Xiaoyu, Zhu, Yanjing, Liu, Hui, Wang, Shi-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149454/ https://www.ncbi.nlm.nih.gov/pubmed/25187702 http://dx.doi.org/10.2147/IJN.S64103

Ejemplares similares

Anti‐Metastatic and Anti‐Angiogenic Activities of Core–Shell SiO(2)@LDH Loaded with Etoposide in Non‐Small Cell Lung Cancer
por: Zhu, Yanjing, et al.
Publicado: (2016)

Cancer Therapy: Anti‐Metastatic and Anti‐Angiogenic Activities of Core–Shell SiO(2)@LDH Loaded with Etoposide in Non‐Small Cell Lung Cancer (Adv. Sci. 11/2016)
por: Zhu, Yanjing, et al.
Publicado: (2016)

Antidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression
por: He, Xiaolie, et al.
Publicado: (2016)

Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants
por: Wu, Chunsheng, et al.
Publicado: (2020)

Enhanced photocytotoxicity of curcumin delivered by solid lipid nanoparticles
por: Jiang, Shan, et al.
Publicado: (2016)

Enhanced tumor uptake, biodistribution and pharmacokinetics of etoposide loaded nanoparticles in Dalton's lymphoma tumor bearing mice
por: Snehalatha, Movva, et al.
Publicado: (2013)

Enhanced intracellular delivery and antibacterial efficacy of enrofloxacin-loaded docosanoic acid solid lipid nanoparticles against intracellular Salmonella
por: Xie, Shuyu, et al.
Publicado: (2017)

Evaluating Cytotoxicity of Hyaluronate Targeted Solid Lipid Nanoparticles of Etoposide on SK-OV-3 Cells
por: Mohammadi Ghalaei, Parviz, et al.
Publicado: (2014)

Preparation of hierarchical mesoporous CaCO(3) by a facile binary solvent approach as anticancer drug carrier for etoposide
por: Peng, Haibao, et al.
Publicado: (2013)

Conversion of the prodrug etoposide phosphate to etoposide in gastric juice and bile.
por: de Jong, R. S., et al.
Publicado: (1997)

The in vitro sustained release profile and antitumor effect of etoposide-layered double hydroxide nanohybrids
por: Qin, Lili, et al.
Publicado: (2013)

Oral bioavailability of cantharidin-loaded solid lipid nanoparticles
por: Dang, Yun-Jie, et al.
Publicado: (2013)

Curcumin-Loaded Solid Lipid Nanoparticles Enhanced Anticancer Efficiency in Breast Cancer
por: Wang, Wenrui, et al.
Publicado: (2018)

Naringenin-loaded solid lipid nanoparticles: preparation, controlled delivery, cellular uptake, and pulmonary pharmacokinetics
por: Ji, Peng, et al.
Publicado: (2016)

Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles
por: Xie, Shuyu, et al.
Publicado: (2011)

Photochemical Internalization of Etoposide Using Dendrimer Nanospheres Loaded with Etoposide and Protoporphyrin IX on a Glioblastoma Cell Line
por: Lin, Martin Hsiu-Chu, et al.
Publicado: (2021)

Enhanced anticancer activity and intracellular uptake of paclitaxel-containing solid lipid nanoparticles in multidrug-resistant breast cancer cells
por: Xu, Wenting, et al.
Publicado: (2018)

Randomized comparison of etoposide pharmacokinetics after oral etoposide phosphate and oral etoposide.
por: de Jong, R. S., et al.
Publicado: (1997)

Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro
por: Siddique, Monowarul M., et al.
Publicado: (2012)

Mitochondria: intracellular sentinels of infections
por: Brokatzky, Dominik, et al.
Publicado: (2022)

Physicochemical and In Vitro Digestion Properties of Curcumin-Loaded Solid Lipid Nanoparticles with Different Solid Lipids and Emulsifiers
por: Yu, Yasi, et al.
Publicado: (2023)

Solid lipid nanoparticles loading with curcumin and dexanabinol to treat major depressive disorder
por: He, Xiao-Lie, et al.
Publicado: (2020)

Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles
por: Xie, Shuyu, et al.
Publicado: (2011)

MgFe‐LDH Nanoparticles: A Promising Leukemia Inhibitory Factor Replacement for Self‐Renewal and Pluripotency Maintenance in Cultured Mouse Embryonic Stem Cells
por: He, Xiaolie, et al.
Publicado: (2021)

Endocytic Uptake of Solid Lipid Nanoparticles by the Nasal Mucosa
por: Al Khafaji, Ammar S., et al.
Publicado: (2021)

PPIP5K1 Suppresses Etoposide-triggered Apoptosis
por: Machkalyan, Gayane, et al.
Publicado: (2016)

Mechanisms for Intracellular Calcium Regulation in Heart : I. Stopped-Flow Measurements of Ca(++) Uptake by Cardiac Mitochondria
por: Scarpa, Antonio, et al.
Publicado: (1973)

Sphingomyelin nanosystems loaded with uroguanylin and etoposide for treating metastatic colorectal cancer
por: Bouzo, Belén L., et al.
Publicado: (2021)

Evaluation of Bacterial Uptake, Antibacterial Efficacy Against Escherichia Coli, and Cytotoxic Effects of Moxifloxacin-loaded Solid Lipid Nanoparticles
por: Kiymaci, Merve Eylul, et al.
Publicado: (2023)

The intracellular bacterium Rickettsia rickettsii exerts an inhibitory effect on the apoptosis of tick cells
por: Martins, Larissa Almeida, et al.
Publicado: (2020)

Characterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants
por: Gao, Li, et al.
Publicado: (2017)

Clinical pharmacokinetics of etoposide during 120 hours continuous infusions in solid tumours.
por: Desoize, B., et al.
Publicado: (1990)

High-dose cyclosporin with etoposide--toxicity and pharmacokinetic interaction in children with solid tumours.
por: Bisogno, G., et al.
Publicado: (1998)

Preparation, Characterization and Pharmacokinetics of Tolfenamic Acid-Loaded Solid Lipid Nanoparticles
por: Xu, Wei, et al.
Publicado: (2022)

Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress
por: Wang, Chen, et al.
Publicado: (2016)

In vitro and intracellular inhibitory activities of nosiheptide against Mycobacterium abscessus
por: Zhu, Rui, et al.
Publicado: (2022)

Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma
por: Wang, Bing, et al.
Publicado: (2015)

Inhibition of protein PMP22 enhances etoposide-induced cell apoptosis by p53 signaling pathway in Gastric Cancer
por: Hou, Jingjing, et al.
Publicado: (2021)

Sustained release Curcumin loaded Solid Lipid Nanoparticles
por: Jourghanian, Parisa, et al.
Publicado: (2016)

Safe administration of etoposide phosphate after hypersensitivity reaction to intravenous etoposide
por: Siderov, J, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_14fs6fr0nc64au7a1lsu4lknh5