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Control of Asymmetric Hopfield Networks and Application to Cancer Attractors
The asymmetric Hopfield model is used to simulate signaling dynamics in gene regulatory networks. The model allows for a direct mapping of a gene expression pattern into attractor states. We analyze different control strategies aimed at disrupting attractor patterns using selective local fields repr...
Autores principales: | Szedlak, Anthony, Paternostro, Giovanni, Piermarocchi, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149479/ https://www.ncbi.nlm.nih.gov/pubmed/25170874 http://dx.doi.org/10.1371/journal.pone.0105842 |
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