Different immunogenicity but similar antitumor efficacy of two DNA vaccines coding for an antigen secreted in different membrane vesicle-associated forms

The induction of an active immune response to control or eliminate tumours is still an unfulfilled challenge. We focused on plasmid DNA vaccines using an innovative approach whereby the antigen is expressed in association with extracellular vesicles (EVs) to facilitate antigen cross-presentation and...

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Detalles Bibliográficos
Autores principales: Sedlik, Christine, Vigneron, James, Torrieri-Dramard, Lea, Pitoiset, Fabien, Denizeau, Jordan, Chesneau, Caroline, de la Rochere, Philippe, Lantz, Olivier, Thery, Clotilde, Bellier, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149746/
https://www.ncbi.nlm.nih.gov/pubmed/25206960
http://dx.doi.org/10.3402/jev.v3.24646

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