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HAUSP, a novel deubiquitinase for Rb – MDM2 the critical regulator
Tumor suppressor retinoblastoma-associated protein (Rb) is an important cell cycle regulator, arresting cells in early G1. It is commonly inactivated in cancers and its level is maintained during the cell cycle. Rb is regulated by various post-translational modifications such as phosphorylation, ace...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149788/ https://www.ncbi.nlm.nih.gov/pubmed/24823443 http://dx.doi.org/10.1111/febs.12843 |